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Transthoracic Echocardiography to Assess Post-Resuscitation Left Ventricular Dysfunction After Acute Myocardial Infarction and Cardiac Arrest in Pigs
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QT dispersion and left ventricular function after stent placement in acute myocardial infarction

Hiroyasu Ueda1, Tomoshige Hayashi, Kei Tsumura

  • 1Department of Cardiology, Ishikiriseiki Hospital, 18-28, Yayoi, Higashiosaka, Osaka, 579-8026, Japan. hiroyasu-sayaka@joy.ocn.ne.jp

International Journal of Cardiology
|November 29, 2005
PubMed

Insights

QT dispersion after acute myocardial infarction (AMI) treatment correlates with left ventricular ejection fraction (LVEF). Measurements at 24 and 48 hours post-procedure are key indicators of long-term LV function.

Area of Science:

  • Cardiology
  • Electrophysiology
  • Cardiovascular Imaging

Background:

  • QT dispersion increases in acute myocardial infarction (AMI).
  • The relationship between QT dispersion and left ventricular (LV) function post-AMI is not fully understood.
  • This study investigates QT dispersion and LV function after successful coronary stenting in AMI patients.

Purpose of the Study:

  • To evaluate the relationship between QT dispersion and LV function.
  • To assess this relationship in patients with AMI who underwent successful coronary stenting.

Main Methods:

  • Seventy-five AMI patients undergoing percutaneous transluminal coronary angioplasty (PTCA) were enrolled.
  • Corrected QT dispersion was measured at multiple time points: pre-PTCA, immediately post-PTCA, 24h, 48h, and 6 months.
  • Left ventricular ejection fraction (LVEF) was assessed by left ventriculography at 6 months post-PTCA.

Main Results:

  • Corrected QT dispersion at 24h and 48h post-PTCA showed significant correlations with LVEF by univariate analysis (p<0.05 and p<0.01).
  • Multiple regression analysis confirmed significant associations between corrected QT dispersion at 24h and 48h post-PTCA and LVEF (R²=0.441, p=0.006 and R²=0.411, p=0.039).
  • No significant association was found between LVEF and corrected QT dispersion measured before, immediately after, or 6 months after PTCA.

Conclusions:

  • Corrected QT dispersion measured 24 and 48 hours after PTCA in AMI patients correlates with LVEF at 6 months post-PTCA.
  • These findings suggest that early post-procedural QT dispersion may serve as a predictor of long-term LV function after successful coronary stenting in AMI.
Abstract

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