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[Cervical spondylodiscitis: one pathogen may hide another].

J Toubiana¹, J Salomon, F Ader

¹Service des maladies infectieuses, département de médecine aiguë spécialisée, université de Versailles, Saint-Quentin-en-Yvelines, CHU Raymond-Poincaré, 104, boulevard Raymond-Poincaré, 92380 Garches, France.

Medecine Et Maladies Infectieuses

|November 29, 2005

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This study reports a rare case of tuberculous spondylodiscitis coinfected with E. coli originating from cholecystitis. The patient successfully recovered with a combination of immobilization, antitubercular drugs, and antibiotics.

Area of Science:

Infectious Diseases
Microbiology
Spinal Surgery

Background:

Tuberculous spondylodiscitis is a significant spinal infection.
Coinfection in spinal infections is uncommon, particularly with mycobacterial and bacterial pathogens.
Enterobacterial infections often stem from gastrointestinal or biliary sources.

Observation:

A 54-year-old male presented with symptoms suggestive of spinal infection.
Intervertebral disc space needle biopsy revealed Mycobacterium tuberculosis and Escherichia coli.
The E. coli infection was traced to a prior cholecystitis.

Findings:

The patient was diagnosed with tuberculous spondylodiscitis coinfected with E. coli.
A comprehensive treatment regimen was initiated, including non-surgical immobilization.

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Antitubercular quadritherapy combined with targeted antibiotic therapy led to patient recovery.

Implications:

This case highlights the potential for unusual polymicrobial infections in the spine.
Effective management requires identifying and treating all causative pathogens.
Further research is needed to understand the epidemiology and treatment of such rare coinfections.