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[Evolution of severe pediatric malaria in Togo between 2000 and 2002]

A D Gbadoé1, M Kini-Caussi, S Koffi

  • 1Service de pédiatrie, CHU-Tokoin, BP 8881, Lomé, Togo. adgbadoe@yahoo.fr

Medecine Et Maladies Infectieuses
|November 29, 2005
PubMed

Insights

Severe malaria in hospitalized children in Togo (2000-2002) predominantly affected those aged 1-5 years. Key findings include increased hemoglobinuria and renal failure, with a 9.7% mortality rate.

Area of Science:

  • Pediatrics
  • Infectious Diseases
  • Tropical Medicine

Context:

  • Severe malaria remains a significant pediatric health concern in sub-Saharan Africa.
  • Hospitalized children in Togo between 2000-2002 were analyzed.
  • The study focused on clinical and evolutive aspects of severe malaria.

Purpose:

  • To analyze the clinical and evolutive features of severe malaria in hospitalized children in Togo.
  • To identify trends in severe malaria presentation and outcomes over a three-year period.

Summary:

  • Malaria represented 4.37% of hospitalizations, with children aged 1-5 years most affected (69.53%).
  • Common clinical forms included anemia (55.7%) and cerebral manifestations.
  • Increased frequencies of hemoglobinuria (17.2%) and renal failure (3%) were observed.
  • Mortality was 9.7%, with deaths often associated with anemia, neurological, or respiratory distress.
  • Neurological sequelae were noted in 2.2% of patients.

Impact:

  • Highlights the persistent burden of severe malaria in young children.
  • Informs clinical management strategies for severe malaria in resource-limited settings.
  • Underscores the need for continued surveillance and intervention for malaria-related morbidity and mortality.

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