Related Experiment Video
Updated: Aug 14, 2026

Demonstrating Hairy and Glabrous Skin Innervation in a 3D Pattern Using Multiple Fluorescent Staining and Tissue Clearing Approaches
Published on: May 20, 2022
Cutaneous innervation: form and function
Anne Louise Oaklander1, Sandra M Siegel
1Department of Anesthesiology, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts, USA. aoaklander@partners.org
Abstract:
It is useful for dermatologists to know about the innervation of the skin because dysfunction of cutaneous neurons can cause symptoms--such as itching, pain, and paresthesias--that are evaluated by dermatologists. We review the innervation of the skin and update readers about recent neuroscientific discoveries.
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