Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Ultraviolet immunosuppression: mechanisms and consequences.

Kaija K Hanneman1, Kevin D Cooper, Elma D Baron

  • 1Department of Dermatology, University Hospitals of Cleveland/Case Western Reserve University, Cleveland, OH 44106, USA.

Dermatologic Clinics
|November 29, 2005
PubMed
Summary

Ultraviolet (UV) radiation exposure suppresses immune functions, a key factor contributing to skin cancer development. Understanding this immune suppression is crucial for effective sun protection strategies.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

The impact of GLP-1 receptor agonists on clinical outcomes and healthcare utilization in hidradenitis suppurativa patients: A retrospective cohort study using TriNetX.

Journal of the American Academy of Dermatology·2025
Same author

Advances in Cutaneous Melanoma Therapy: The Emerging Role of CDK4/6 Inhibitors.

Pharmacological research·2025
Same author

NF-κB c-Rel is a critical regulator of TLR7-induced inflammation in psoriasis.

EBioMedicine·2024
Same author

Holistic review increases inclusion of underrepresented-in-medicine applicants in dermatology residency recruitment.

Archives of dermatological research·2024
Same author

Maximizing the potential of biobanks in dermatology research.

Journal of dermatological science·2024
Same author

Control of dermatomyositis skin disease activity lags behind control of muscles disease activity during the early treatment stages of classic dermatomyositis: A retrospective, single-centre study.

Skin health and disease·2024

Area of Science:

  • Photobiology
  • Immunology
  • Dermatology

Background:

  • Solar radiation exposure causes acute and chronic detrimental health effects.
  • Ultraviolet (UV) radiation is known to suppress immune functions.
  • UV-induced immune suppression is implicated in the development of skin cancers.

Purpose of the Study:

  • To highlight the significance of UV radiation's impact on immune function.
  • To emphasize the link between UV immune suppression and cutaneous malignancies.
  • To underscore the importance of sun protection strategies.

Main Methods:

  • Review of existing scientific literature on UV radiation and immune response.
  • Analysis of the role of UV radiation in immune suppression.
  • Correlation of UV-induced immune suppression with skin cancer growth.

Related Experiment Videos

Main Results:

  • UV radiation exposure leads to suppression of the immune system.
  • This immune suppression is a significant factor in the pathogenesis of melanoma and nonmelanoma skin cancer.
  • Mechanisms of UV immune suppression are still under investigation but the link is established.

Conclusions:

  • UV-induced immune suppression is a critical factor in skin cancer development.
  • Effective sun protection strategies are essential to mitigate risks associated with UV exposure.
  • Further research into the mechanisms of UV immune suppression is warranted.