Related Experiment Video
Updated: Aug 14, 2026

A Murine Model of Hemodialysis Access-Related Hand Dysfunction
Published on: May 31, 2022
Haemodialysis vascular access problems in Canada: results from the Dialysis Outcomes and Practice Patterns Study
David C Mendelssohn1, Jean Ethier, Stacey J Elder
1Division of Nephrology, Humber River Regional Hospital, University of Toronto, Weston, ON, Canada. dmendelssohn@hrrh.on.ca
Insights
Canadian hemodialysis patients frequently use central venous catheters, despite guidelines recommending arteriovenous fistulas. This study highlights delays and resource issues impacting fistula creation, urging improved vascular access strategies.
Area of Science:
- Nephrology
- Vascular Surgery
- Health Services Research
Background:
- The native arteriovenous fistula (AVF) is the optimal vascular access for chronic maintenance hemodialysis (HD).
- Vascular access practice patterns in Canada were examined using data from the Dialysis Outcomes and Practice Patterns Study (DOPPS II).
Purpose of the Study:
- To report Canadian vascular access practice patterns.
- To compare Canadian practices with those in Europe and the USA.
- To identify factors contributing to vascular access outcomes in Canada.
Main Methods:
- Prospective, observational study of a representative random sample of 20 Canadian HD facilities and patients.
- Data collected between 2002-2004 as part of the DOPPS II study.
- Canadian results compared with European and USA data.
Main Results:
- AVF use in Canadian prevalent (53%) and incident (26%) patients was below recommended guidelines and lower than in Europe.
- Central venous catheter use was significantly higher in Canada (prevalent 33%, incident 70%) compared to Europe and the USA.
- Longer delays in permanent vascular access creation in Canada (61.7 days) were associated with fewer access surgeons and less surgical time per patient.
Conclusions:
- Canadian chronic HD patients disproportionately rely on central venous catheters, associated with adverse outcomes.
- There is a critical need for increased education on AVF priority among healthcare professionals and policymakers.
- Securing human and financial resources is essential to enhance timely AVF creation rates in Canada.
Background:
The optimal vascular access for chronic maintenance haemodialysis (HD) is the native arteriovenous fistula (AVF). Vascular access practice patterns are reported for a Canadian cohort of patients from the Dialysis Outcomes and Practice Patterns Study (DOPPS II).
Methods:
DOPPS II is a prospective, observational study in 12 countries, including Canada. A representative random sample of 20 Canadian HD facilities and patients within those units were studied during 2002-2004. Canadian results were compared with those found in Europe and the USA.
Results:
AVF use in Canadian prevalent (53%) and incident (26%) patients was lower than Canadian guidelines recommend (60%), and lower than in Europe [prevalent (74%), incident (50%)]. Despite 85% of Canadian HD patients having seen a nephrologist for > 1 month prior to starting dialysis, central venous catheter use in Canada (33% in prevalent patients, 70% in incident patients) was much higher than in Europe (prevalent 18%, incident 46%) and slightly higher than in the USA (prevalent 25%, incident 66%). This pattern is contrary to the preferences of Canadian medical directors and vascular access surgeons. The typical time from referral until permanent vascular access creation is substantially longer in Canada (61.7 days) than in Europe (29.4 days) or the USA (16 days). This longer delay time and higher catheter use in Canada may be a consequence of the significantly lower number of access surgeons per 100 HD patients in Canada (2.9) compared with the USA (8.1) and Europe (4.6). Furthermore, the median hours per week devoted to vascular access-related surgery per 100 patients is substantially lower in Canada (0.027 h) compared with the USA (0.082 h) and Europe (0.059 h).
Conclusion:
These findings suggest that Canadian chronic HD patients often rely on central venous catheters for vascular access, despite their known association with numerous detrimental outcomes in HD. Nephrologists, vascular access surgeons, interventional radiologists, other physicians and health care funding bodies must be more broadly educated about the priority of AVF creation as the preferred vascular access for chronic HD patients. They must work together to secure both the human and financial resources and other health care system enhancements to increase AVF creation rates in a timely manner.
Related Concept Videos
Hemodialysis II: Procedure and Complications
Hemodialysis I: Introduction
Hemodialysis III: Nursing Management
Peritoneal Dialysis II: Peritoneal Dialysis Systems and Complications
Dialysis
Acute kidney injury develops suddenly and can be caused by pre-renal causes (e.g., hypovolemia, shock), intrinsic renal causes (e.g., acute tubular necrosis), or post-renal causes (e.g., urinary obstruction). In contrast, chronic renal failure progresses gradually over time and is often...
Peritoneal Dialysis III: Nursing Management
