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Published on: September 30, 2021

Successful use of recombinant factor VIIa in a patient with intractable bleeding during extracorporeal membrane

S Brose1, H Sirbu, M Engel

  • 1Department of Cardiac Surgery, Heart Center Dresden, University of Dresden, Dresden, Germany. s.brose@herzzentrum-dresden.com

The Thoracic and Cardiovascular Surgeon
|November 29, 2005
PubMed

Bleeding is still the most common complication during extracorporeal membrane oxygenation (ECMO) for temporary cardio-circulatory support. We present a case of a young man suffering from intractable hemorrhage during ECMO support, who was pre-treated with glycoprotein IIb/IIIa receptor antagonist Tirofiban due to a suspicion of myocardial ischemia. After failure of conventional hemostatic means, hemostasis was achieved by the donation of recombinant Factor VIIa (rFVIIa). Aspects of bleeding control during extracorporeal circulatory support, the use of Tirofiban and rFVIIa are discussed.

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