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Updated: Aug 7, 2026

Engineered Vascularized Muscle Flap
Published on: January 11, 2016
Acute repair of a full-thickness right ventricular defect with a composite myofascial pedicle flap
D A Ladin1, D P Smith, P H Izenberg
1Department of Plastic and Reconstructive Surgery, University of Michigan Medical Center, Ann Arbor.
Abstract:
A full-thickness defect of the right ventricle presented acutely after mediastinitis and sternal dehiscence. This developed 29 days after bilateral internal mammary artery harvest for coronary artery bypass grafting. The defect was managed successfully with a pedicled left rectus abdominis muscle flap using an attached island of the anterior rectus sheath for endocardial lining. The vascular anatomic basis for viability of the rectus abdominis muscle flap after internal mammary artery harvest is derived primarily from musculophrenic, lumbar, lower sixth intercostal, and subcostal artery communications. In addition, the advantages of a myofascial pedicle flap for reconstruction of full-thickness cardiac defects are its ready availability and a strong anterior fascial sheath that can be used as a neoendocardial lining. The patient did well and remains asymptomatic after 3 years.

