Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Proteins implicated in sperm capacitation.

Kasturi Mitra1, S Shivaji

  • 1Centre for Cellular and Molecular Biology, Uppal Road, Hyderabad 500 007, India.

Indian Journal of Experimental Biology
|November 30, 2005
PubMed
Summary

Spermatozoa undergo capacitation, a crucial maturation process in the female reproductive tract, essential for fertilization. This review explores the molecular mechanisms driving these vital changes in male gametes.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Small extracellular vesicle signaling and mitochondrial transfer reprogram T helper cell function in human asthma.

Nature communications·2026
Same author

Quantitative analyses of single mitochondrial components reveal an early role of small-mitochondrial-networks in priming neoplasticity.

bioRxiv : the preprint server for biology·2025
Same author

Small Extracellular Vesicle Signaling and Mitochondrial Transfer Reprograms T Helper Cell Function in Human Asthma.

bioRxiv : the preprint server for biology·2024
Same author

Significance of quantitative analyses of the impact of heterogeneity in mitochondrial content and shape on cell differentiation.

Open biology·2024
Same author

The interplay between sex, time of day, fasting status, and their impact on cardiac mitochondrial structure, function, and dynamics.

Scientific reports·2023
Same author

Enrichment of carcinogen-driven "mitochondria-primed" human skin stem cells and their identification using single-cell analyses.

STAR protocols·2023

Area of Science:

  • Reproductive Biology
  • Gamete Physiology
  • Cellular Signaling

Background:

  • Spermatozoa require a period within the female reproductive tract before they can fertilize an oocyte.
  • This essential maturation process was termed 'Capacitation' by Austin.
  • Understanding capacitation is key to reproductive science.

Purpose of the Study:

  • To review the key features of sperm capacitation.
  • To survey the molecular and cellular players involved in capacitation.
  • To elucidate the signal transduction pathways governing sperm maturation.

Main Methods:

  • Literature review of capacitation research.
  • Analysis of molecular and cellular changes during capacitation.
  • Survey of signal transduction pathways.

Main Results:

  • Capacitation involves cumulative molecular, cellular, and physiological changes.
  • Novel signal transduction pathways guide capacitation.
  • These changes are necessary for spermatozoa to achieve fertilizing competence.

Conclusions:

  • Capacitation is a complex, regulated process essential for male fertility.
  • Further research into signal transduction pathways will deepen understanding.
  • This review provides a framework for studying sperm capacitation mechanisms.

Related Experiment Videos