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Porocarcinoma arising in pigmented hidroacanthoma simplex
Tetsuya Ueo1, Kenji Kashima, Tsutomu Daa
1Department of Pathology, Faculty of Medicine, Oita University, Oita, Japan. tueo@med.oita-u.ac.jp
The American Journal of Dermatopathology
|November 30, 2005
Summary
This study details a rare case of porocarcinoma developing from pigmented hidroacanthoma simplex (HAS) with amyloid deposits. The findings highlight an unusual malignant transformation pathway for this benign skin tumor.
Area of Science:
- Dermatopathology
- Oncology
- Histopathology
Background:
- Hidroacanthoma simplex (HAS), or intraepidermal poroma, is a rare benign skin tumor.
- Malignant transformation of HAS into porocarcinoma is infrequently reported.
Observation:
- An 80-year-old Japanese man presented with a long-standing cutaneous tumor on his left buttock.
- The tumor exhibited distinct pigmented plaque and depigmented papule with erosion components.
Findings:
- Histologic analysis revealed pigmented HAS with amyloid deposits in the pigmented area.
- The depigmented area showed markedly atypical cells consistent with porocarcinoma, arising from the HAS.
Implications:
- This case presents an unusual instance of porocarcinoma arising in a pigmented HAS with secondary amyloid deposition.
- The findings contribute to understanding the spectrum of HAS malignant transformation.
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