Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Measuring Single-Cell Aging with an Imaging-based Biomarker of Chromatin and Epigenetic Aging09:10

Measuring Single-Cell Aging with an Imaging-based Biomarker of Chromatin and Epigenetic Aging

208
The protocol presents the imaging and computational workflow to extract and validate imaging-based chromatin and epigenetic age...
208
Electrostatic Method to Remove Particulate Organic Matter from Soil04:40

Electrostatic Method to Remove Particulate Organic Matter from Soil

5.2K
Removing recently deposited and incompletely decomposed plant material from soil samples reduces the influence of temporary seasonal inputs on soil organic carbon measurements. Attraction to an electrostatically charged surface can be used to quickly remove a substantial amount of particulate organic...
5.2K
Improving Infrared Spectroscopy Characterization of Soil Organic Matter with Spectral Subtractions08:57

Improving Infrared Spectroscopy Characterization of Soil Organic Matter with Spectral Subtractions

13.2K
SOM underlies many soil functions and processes, but its characterization by FTIR spectroscopy is often challenged by mineral interferences. The described method can increase the utility of SOM analysis by FTIR spectroscopy by subtracting mineral interferences in soil spectra using empirically obtained mineral reference...
13.2K
Production and Measurement of Organic Particulate Matter in a Flow Tube Reactor13:29

Production and Measurement of Organic Particulate Matter in a Flow Tube Reactor

8.0K
This paper describes the operation procedure for the flow tube reactor and related data collection. It shows the protocols for setting the experiments, recording data and generating the number-diameter distribution as well as the particle mass information, which gives useful information about chemical and physical properties of the organic...
8.0K
Production and Measurement of Organic Particulate Matter in the Harvard Environmental Chamber09:46

Production and Measurement of Organic Particulate Matter in the Harvard Environmental Chamber

7.7K
This paper describes operation procedures for the Harvard Environmental Chamber (HEC) and related instrumentation for measuring gaseous and particle species. The environmental chamber is used to produce and study secondary organic species produced from the organic precursors, especially related to atmospheric organic particulate matter.
7.7K
Understanding Dissolved Organic Matter Biogeochemistry Through In Situ Nutrient Manipulations in Stream Ecosystems09:38

Understanding Dissolved Organic Matter Biogeochemistry Through In Situ Nutrient Manipulations in Stream Ecosystems

11.0K
Dissolved organic matter provides an important source of energy and nutrients to stream ecosystems. Here we demonstrate a field-based method to manipulate the ambient pool of dissolved organic matter in situ through easily replicable nutrient...
11.0K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

DHHC3 interferes with antitumor immunity in melanoma cells.

Oncotarget·2026
Same author

Antioxidant and Anticancer Functions of Protein Acyltransferase DHHC3.

Antioxidants (Basel, Switzerland)·2022
Same author

Antioxidant functions of DHHC3 suppress anti-cancer drug activities.

Cellular and molecular life sciences : CMLS·2020
Same author

Integrin-independent support of cancer drug resistance by tetraspanin CD151.

Cellular and molecular life sciences : CMLS·2019
Same author

Multiple pro-tumor roles for protein acyltransferase DHHC3.

Oncoscience·2018
Same author

Protein Acyltransferase DHHC3 Regulates Breast Tumor Growth, Oxidative Stress, and Senescence.

Cancer research·2017

Related Experiment Video

Updated: Feb 7, 2026

Production and Measurement of Organic Particulate Matter in a Flow Tube Reactor
13:29

Production and Measurement of Organic Particulate Matter in a Flow Tube Reactor

Published on: December 15, 2018

8.0K

Tetraspanin functions and associated microdomains.

Martin E Hemler1

  • 1Dana-Farber Cancer Institute and Harvard Medical School, 44 Binney Street, Boston, Massachusetts 02115, USA. Martin_Hemler@dfci.harvard.edu

Nature Reviews. Molecular Cell Biology
|November 30, 2005
PubMed
Summary

Tetraspanins, small cell-surface proteins, have been historically overlooked. New genetic and cell biology research reveals their crucial roles in cellular processes like signaling and motility.

Area of Science:

  • Cell Biology
  • Molecular Biology
  • Protein Biochemistry

Background:

  • Tetraspanins are cell-surface proteins present on most cell types.
  • Their small size and location within the cell membrane have led to them being understudied.
  • Recent advances highlight their potential importance in cellular functions.

Purpose of the Study:

  • To re-evaluate the significance of tetraspanin proteins.
  • To integrate new genetic, cell biology, and biochemical data on tetraspanins.
  • To establish a framework for understanding tetraspanin functions in cellular regulation.

Main Methods:

  • Analysis of emerging genetic evidence.
  • Integration of new cell biology insights.
  • Review of tetraspanin signaling and biochemistry.

More Related Videos

Production and Measurement of Organic Particulate Matter in the Harvard Environmental Chamber
09:46

Production and Measurement of Organic Particulate Matter in the Harvard Environmental Chamber

Published on: November 18, 2018

7.7K
Understanding Dissolved Organic Matter Biogeochemistry Through In Situ Nutrient Manipulations in Stream Ecosystems
09:38

Understanding Dissolved Organic Matter Biogeochemistry Through In Situ Nutrient Manipulations in Stream Ecosystems

Published on: October 29, 2016

11.0K

Related Experiment Videos

Last Updated: Feb 7, 2026

Production and Measurement of Organic Particulate Matter in a Flow Tube Reactor
13:29

Production and Measurement of Organic Particulate Matter in a Flow Tube Reactor

Published on: December 15, 2018

8.0K
Production and Measurement of Organic Particulate Matter in the Harvard Environmental Chamber
09:46

Production and Measurement of Organic Particulate Matter in the Harvard Environmental Chamber

Published on: November 18, 2018

7.7K
Understanding Dissolved Organic Matter Biogeochemistry Through In Situ Nutrient Manipulations in Stream Ecosystems
09:38

Understanding Dissolved Organic Matter Biogeochemistry Through In Situ Nutrient Manipulations in Stream Ecosystems

Published on: October 29, 2016

11.0K

Main Results:

  • Tetraspanins are increasingly recognized for their roles beyond simple structural components.
  • New data supports their involvement in complex cellular signaling pathways.
  • Their regulation of cellular processes like motility is becoming clearer.

Conclusions:

  • Tetraspanins are critical regulators of fundamental cellular processes.
  • Further research into tetraspanins is warranted due to their broad implications.
  • Understanding tetraspanins offers new avenues for exploring cell signaling and motility.