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Leuconostoc bacteraemia.

M L Ling1

  • 1Department of Pathology, Singapore General Hospital.

Singapore Medical Journal
|June 1, 1992
PubMed
Summary
This summary is machine-generated.

Leuconostoc species, a bacterium, can be a pathogen in immunocompromised individuals. This study questions its clinical significance when found in blood cultures, especially when other organisms are present.

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Area of Science:

  • Microbiology
  • Clinical Medicine
  • Infectious Diseases

Background:

  • Leuconostoc species are gram-positive bacteria.
  • They are typically moderately susceptible to ampicillin and penicillin but resistant to vancomycin.
  • These bacteria are considered potential pathogens, particularly in immunocompromised hosts.

Purpose of the Study:

  • To investigate the clinical significance of Leuconostoc species isolated from blood cultures.
  • To determine when Leuconostoc species infections warrant specific antimicrobial therapy.

Main Methods:

  • Retrospective analysis of 28 Leuconostoc isolates from blood cultures (1989-1990).
  • Review of clinical history and patient outcomes for 19 patients with Leuconostoc bacteremia.
  • Comparison of outcomes in patients with Leuconostoc isolated alone versus with other microorganisms.

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Main Results:

  • Five patients recovered without antimicrobial therapy.
  • In eight patients, Leuconostoc species were isolated concurrently with other organisms.
  • The study highlights the ambiguity in determining clinical significance for Leuconostoc bacteremia.

Conclusions:

  • The clinical significance of Leuconostoc species in blood cultures is often unclear.
  • Further investigation is needed to establish clear diagnostic criteria for Leuconostoc infections.
  • Distinguishing colonization from true infection is crucial for appropriate patient management.