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Published on: April 17, 2012
Radiotherapy in the treatment of dermatofibrosarcoma protuberans
Roi Dagan1, Christopher G Morris, Robert A Zlotecki
1Department of Radiation Oncology, University of Florida College of Medicine, Gainesville, FL, USA.
Objective:
To evaluate the role of postoperative radiotherapy (RT) for patients with dermatofibrosarcoma protuberans (DFSP).
Methods And Materials:
Ten patients were treated with surgery and postoperative RT and had follow-up from 21 to 185 months. Nine patients had DFSP and 1 patient had a fibrosarcomatous component (DFSP-FS). No patient had gross disease at the time of RT.
Results:
Nine patients with DFSP remained disease free after surgery and postoperative RT. The patient with DFSP-FS experienced a local recurrence after surgery, external beam RT, and a brachytherapy boost, and died with disease. There were no severe complications.
Conclusion:
Postoperative RT may reduce the risk of local recurrence in patients with DFSP who have a high risk of residual disease after surgery.
