Related Experiment Video
Updated: Aug 14, 2026

Accessing the Subdural Space of the Rodent Spinal Cord for Treatment Delivery
Published on: August 8, 2025
[Spinal anaesthesia]
1Klinik für Anästhesiologie und Operative Intensivmedizin, Zentralklinikum Augsburg, Stenglinstrasse 2, 86156 Augsburg. gerheuser@anaesthesie-klinikum-augsburg.de
Abstract:
In spinal anaesthesia, surgical analgesia and in most cases motor block is achieved by injecting one or more drugs into the cerebrospinal fluid. As one of the earliest methods of anaesthesia it was introduced into clinical practice in the late nineteenth century. Although later on it was more or less replaced by "modern" general anaesthesia, it has regained popularity due to its benefits for certain patient populations. In spite of being a technically simple procedure, performing spinal anaesthesia requires a sound knowledge of applied physiology and pharmacology, especially in high-risk groups such as pregnant women or former preterm babies. For some patients even under anticoagulant therapy, spinal anaesthesia might be the best option, considering the individual risk of alternative methods.
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