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Hepatitis C virus comes full circle: production of recombinant infectious virus in tissue culture

Jan Martin Berke1, Darius Moradpour

  • 1Division of Gastroenterology and Hepatology, Centre Hospitalier Universitaire Vaudois, University of Lausanne, Switzerland.

Hepatology (Baltimore, Md.)
|December 1, 2005
PubMed
Abstract

No abstract available in PubMed .

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Hepatitis is an inflammatory condition of the liver most commonly caused by hepatotropic viruses (A–E), though non-infectious causes such as alcohol and drugs also exist.Hepatitis AHepatitis A virus (HAV) is a non-enveloped RNA virus of the Picornaviridae family. It is primarily transmitted via the fecal-oral route, typically through ingestion of contaminated food or water. After ingestion, HAV enters the bloodstream through the oropharynx or intestinal epithelium and reaches the liver. The...