Laser photocoagulation for treatment of experimental aneurysms

Twenty-five autologous, artificially implanted venous and arterial aneurysms were treated by argon laser photocoagulation. Sequential angiographic follow-up studies and final histologic studies demonstrated complete secondary occlusion in 11 cases, significant reduction of the aneurysm lumen in 10 cases, and no change in 4 cases. Delayed secondary occlusion appears to involve an active biologic process with progressive fibroblastic proliferation in the aneurysm wall.