Related Experiment Video
Updated: Aug 14, 2026

Quadruple-Checkerboard: A Modification of the Three-Dimensional Checkerboard for Studying Drug Combinations
Published on: July 24, 2021
Antibacterial cleaning products and drug resistance
Allison E Aiello1, Bonnie Marshall, Stuart B Levy
1University of Michigan School of Public Health, Ann Arbor, Michigan 48104-2548, USA. aielloa@umich.edu
Abstract:
We examined whether household use of antibacterial cleaning and hygiene products is an emerging risk factor for carriage of antimicrobial drug-resistant bacteria on hands of household members. Households (N = 224) were randomized to use of antibacterial or nonantibacterial cleaning and hygiene products for 1 year. Logistic regression was used to assess the influence of antibacterial product use in homes. Antibacterial product use did not lead to a significant increase in antimicrobial drug resistance after 1 year (odds ratio 1.33, 95% confidence interval 0.74-2.41), nor did it have an effect on bacterial susceptibility to triclosan. However, more extensive and longer term use of triclosan might provide a suitable environment for emergence of resistant species. Further research on this issue is needed.
Related Concept Videos
Clinical Significance of Antibiotic Resistance
Development of Antibiotic Resistance
Mechanism of Antibiotic Resistance in MRSA
Antibiotic Selection
Chemical Agents for Microbial Control
Antimicrobial Effectiveness
