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Myocarditis Outbreak among Adults, Illinois, 2003

Gregory D Huhn1, Cindy Gross, David Schnurr

  • 1Centers for Disease Control and Prevention, Atlanta, Georgia , USA. Gregory_Huhn@rush.edu

Insights

An outbreak of myocarditis in Illinois adults was investigated. Diagnostic tests for enterovirus and adenovirus in patient samples were inconclusive, indicating a need for improved diagnostic methods.

Area of Science:

  • Cardiology
  • Infectious Diseases
  • Pathology

Background:

  • An unexplained outbreak of myocarditis occurred in Illinois adults in 2003.
  • Myocarditis is an inflammation of the heart muscle, potentially leading to serious cardiac complications.

Purpose of the Study:

  • To investigate the cause of the 2003 myocarditis outbreak in Illinois.
  • To evaluate diagnostic testing for enterovirus and adenovirus in affected patients.

Main Methods:

  • Diagnostic testing of myocardial tissues from three patients.
  • Comprehensive testing for enterovirus and adenovirus in other patient specimens.

Main Results:

  • Diagnostic tests on myocardial tissues were inconclusive.
  • Comprehensive enterovirus and adenovirus testing yielded inconclusive results.

Conclusions:

  • Current diagnostic techniques were insufficient to identify the cause of the myocarditis outbreak.
  • Improved specimen collection and enhanced diagnostic methods are necessary for future investigations of idiopathic cardiomyopathy and related outbreaks.

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