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Related Experiment Videos

Initial and repeat testing for chlamydia during pregnancy.

Joseph M Miller1, Robert T Maupin, Malanda Nsuami

  • 1Department of Obstetrics, Louisiana State University Health Sciences Center, New Orleans, LA 70112, USA. jmille@lsuhsc.edu

The Journal of Maternal-Fetal & Neonatal Medicine : the Official Journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians
|December 2, 2005
PubMed
Summary

Repeat chlamydia testing in late pregnancy is crucial for high-risk women. This identified a significant prevalence of infection and reinfection, highlighting the need for ongoing screening during prenatal care.

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Area of Science:

  • Obstetrics and Gynecology
  • Infectious Diseases
  • Public Health

Background:

  • Chlamydia trachomatis is a common sexually transmitted infection.
  • Untreated chlamydia in pregnancy can lead to adverse outcomes.

Purpose of the Study:

  • To determine the prevalence of chlamydia in late pregnancy among women with an initial negative test.
  • To identify factors associated with chlamydial carriage in this population.

Main Methods:

  • Retrospective cohort study of 752 prenatal patients from an inner-city clinic.
  • Analysis of initial and late (34 weeks gestational age) chlamydia test results.
  • Statistical analysis including chi-squares, odds ratios, and t-tests.

Main Results:

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  • Chlamydia prevalence was 17.8%, with 3.9% positive only on the late test.
  • Treatment failure or reinfection occurred in 13.3% of cases.
  • Factors associated with carriage included age <19, gonorrhea, lower gravidity/parity, and unmarried status.

Conclusions:

  • Repeat chlamydia screening in late pregnancy is appropriate for high-risk populations.
  • Gonorrhea carriage and young maternal age are key indicators for cervicitis.