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Related Experiment Videos

Olivocochlear activity and temporary threshold shift-susceptibility in humans.

W Wagner1, G Heppelmann, M Kuehn

  • 1Department of Otorhinolaryngology, University of Tuebingen, Tuebingen, Germany. w.wagner@med.uni-tuebingen.de

The Laryngoscope
|December 2, 2005
PubMed
Summary

Contralateral suppression of otoacoustic emissions (CS of OAE) is a reliable tool for measuring medial olivocochlear efferent activity in humans. However, CS of OAE does not predict individual susceptibility to temporary threshold shifts from noise exposure.

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Area of Science:

  • Auditory Neuroscience
  • Otoacoustic Emissions
  • Human Auditory Physiology

Background:

  • Animal studies indicate medial olivocochlear efferent activity offers cochlear noise protection.
  • The existence and role of these protective effects in humans remain unconfirmed.
  • Contralateral suppression (CS) of otoacoustic emissions (OAE) serves as an indirect measure of olivocochlear activity.

Purpose of the Study:

  • To investigate the human equivalent of noise-protective medial olivocochlear efferent effects.
  • To assess the reliability of contralateral suppression (CS) of distortion product otoacoustic emissions (DPOAE) in humans.
  • To determine if CS of DPOAE can predict individual susceptibility to temporary threshold shifts (TTS) from impulse noise.

Main Methods:

  • Measured input/output functions of DPOAE with and without contralateral white noise stimulation in 94 normal-hearing males.

Related Experiment Videos

  • Utilized a 'scissor paradigm' with varying sound pressure levels (L2) and frequencies (f2) for DPOAE measurement.
  • Assessed TTS susceptibility in 83 subjects via pure tone audiometry before and after shooting exercises.

    • Main Results:

    • CS of DPOAE demonstrated good test-retest repeatability, confirming its reliability as an audiological tool.
    • CS was greatest at lower stimulus levels and varied across tested frequencies, with peaks at 2 kHz.
    • No significant correlation was found between the degree of CS and individual susceptibility to TTS.

    Conclusions:

    • CS of DPOAE is a reliable audiological measure but does not predict susceptibility to mild noise-induced temporary threshold shifts in humans.
    • Further longitudinal studies are needed to explore the link between medial olivocochlear bundle activity and permanent threshold shifts.
    • The ultimate goal is to develop a diagnostic tool for predicting individual noise vulnerability and preventing noise-induced hearing loss.