Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Predictors of dyadic adjustment in multiple sclerosis.

Kristin E King1, Peter A Arnett

  • 1Psychology Department, College of the Liberal Arts, The Pennsylvania State University, University Park 16802-3105, USA.

Multiple Sclerosis (Houndmills, Basingstoke, England)
|December 3, 2005
PubMed
Summary

Depression and fatigue significantly impact relationship quality for multiple sclerosis (MS) patients. Addressing depression may improve dyadic adjustment in individuals with MS.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Contextualizing racial differences in baseline neuropsychological assessment of collegiate athletes.

Journal of the International Neuropsychological Society : JINS·2026
Same author

Symptom clusters and cognitive changes: predictors of recovery timelines following concussion in college athletes.

Journal of clinical and experimental neuropsychology·2026
Same author

Quality of Life, Self-Reported Cognitive Difficulties, and Performance-Based Cognitive Problems in Multiple Sclerosis: What's Sleep Got to Do With It?

Archives of clinical neuropsychology : the official journal of the National Academy of Neuropsychologists·2026
Same author

Get Your Brain in the Game: Using Machine Learning to Predict Recovery Timelines Following Sports-Related Concussion.

Archives of clinical neuropsychology : the official journal of the National Academy of Neuropsychologists·2025
Same author

Depressive Symptoms, Sleep Complaints, and Cognitive Performance: Examining the Mediating Role of Sleep in College Athletes.

Archives of clinical neuropsychology : the official journal of the National Academy of Neuropsychologists·2025
Same author

Coping is a moderator of relationships between cognitive fatigue and cognitive variability in multiple sclerosis.

Journal of the International Neuropsychological Society : JINS·2025

Area of Science:

  • Neuroscience
  • Psychology
  • Social Science

Background:

  • Multiple sclerosis (MS) is typically diagnosed during young adulthood and middle age, a critical period for forming significant relationships.
  • Dyadic adjustment is crucial for individuals with MS, yet factors contributing to relationship difficulties remain understudied.
  • Common MS symptoms like depression, fatigue, and cognitive dysfunction may affect interpersonal relationships.

Purpose of the Study:

  • To investigate the association between MS-related symptoms (depression, fatigue, cognitive dysfunction) and dyadic adjustment in MS patients.
  • To identify which specific MS sequelae are most predictive of relationship problems.
  • To explore the bidirectional relationship between depression and dyadic adjustment in MS.

Main Methods:

  • Sixty-four individuals diagnosed with MS and 49 of their significant others participated in the study.
  • Participants completed assessments measuring depression symptoms, fatigue, cognitive functioning, and dyadic adjustment.
  • Statistical analyses, including correlation and stepwise regression, were used to examine the relationships between variables.

Main Results:

  • Patient-reported dyadic adjustment correlated negatively with depression and fatigue.
  • Significant other-reported dyadic adjustment correlated negatively with patient depression and fatigue, and positively with executive functioning impairments.
  • Depression emerged as the sole significant predictor of dyadic adjustment, irrespective of the reporter (patient or significant other).

Conclusions:

  • Depression is a key factor associated with impaired dyadic adjustment in multiple sclerosis patients.
  • Interventions targeting depression in MS patients may lead to improved relationship quality.
  • The findings suggest a potential therapeutic benefit of addressing relationship issues to alleviate depressive symptoms in MS.

Related Experiment Videos