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Anti-lymphocyte antibodies generated in animals immunised with Theileria annulata-infected cells

M Kachani1, R L Spooner

  • 1Département de Parasitologie, Institut Agronomique et Vétérinaire Hassan II, Rabat Instituts, Morocco.

Veterinary Immunology and Immunopathology
|June 1, 1992
PubMed

Complement fixing antibodies were measured in sera from animals immunised with either Theileria annulata sporozoites or autologous or allogeneic schizont-infected mononuclear cells using a complement-mediated micro-cytotoxicity test. The test demonstrated the presence of anti-lymphocyte antibodies in allogeneic cell-immunised animals, which were not detectable in autologous cell- or sporozoite-immunised animals; also that these antibodies were directed to T. annulata-infected and (MHC) class I antigens. Their potential importance in repeated immunisations is discussed.

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