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Female puberty: clinical implications for the use of prolactin-modulating psychotropics
Amy L Becker1, C Neill Epperson
1Yale University School of Medicine, Child Study Center, 230 South Frontage Road, New Haven, CT 06520, USA. alb1655@aol.com
Abstract:
During puberty, girls may present with psychiatric illness necessitating treatment with psychotropic medications. Pubertal girls are especially vulnerable to medication-associated adverse events. Atypical antipsychotics and antidepressants have the potential to elevate prolactin levels, altering pubertal progression. Selection of prolactin-sparing atypical antipsychotics is recommended, as is treatment with the lowest effective dose of selective serotonin reuptake inhibitors. Monitoring of serum prolactin levels may be necessary.
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