Splenectomy in haematology--a 5-year single centre experience

Area of Science:

• Hematologic oncology
• Surgical pathology
• Gastrointestinal surgery

Background:

• Splenectomy is a crucial intervention for various hematologic disorders.
• Understanding indications and outcomes is vital for patient management.
• Evaluating surgical approaches (open vs. laparoscopic) is essential.

Purpose of the Study:

• To define indications for splenectomy in hematologic conditions.
• To assess the outcomes of splenectomy in these patients.
• To compare open versus laparoscopic splenectomy approaches.

Main Methods:

• Retrospective review of clinical records for patients undergoing splenectomy.
• Inclusion of consecutive patients from an academic private sector center.
• Data collection on survival, operating time, spleen size, histopathology, blood product requirements, complications, and costs.

Main Results:

• Two deaths in 69 patients (2.9% mortality).
• Common indications include immune thrombocytopenia (41%) and leukemia (19%).
• Open splenectomy was used for larger spleens and bleeding disorders; laparoscopic for others. Mean operative times: 83 min (open) vs. 251 min (laparoscopic).

Conclusions:

• Appropriate patient stratification and surgical technique optimize hemostasis, reducing blood product needs.
• Morbidity and mortality are not significantly influenced by underlying pathology or surgical approach.
• Surgical outcomes correlate with procedural volume, adherence to protocols, and standardized postoperative care.