Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Vitrectomy for persistent panuveitis in Behçet's disease.

Jae Kyoun Ahn1, Hum Chung, Hyeong Gon Yu

  • 1Department of Ophthalmology, Seoul National University of College Medicine, and Seoul National University Hospital, Clinical Research Institute, Seoul Artificial Eye Center, Seoul, Korea.

Ocular Immunology and Inflammation
|December 3, 2005
PubMed
Summary

Vitrectomy offers a safe and effective treatment for vitreoretinal complications in Behçet's disease patients with persistent panuveitis, improving vision and inflammation control. However, outcomes are poor for those with optic disc neovascularization.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

International consensuses and guidelines on managing ocular Behçet's disease by the Academy of Asia-Pacific Professors of Ophthalmology (AAPPO), the Asia-Pacific Vitreo-Retina Society (APVRS), the Asia-Pacific Society of Ocular Inflammation and Infection (APSOII) and the Academia Retina Internationalis (ARI).

Asia-Pacific journal of ophthalmology (Philadelphia, Pa.)·2025
Same author

A pilot study : retinal sensitivity change in neovascular age-related macular degeneration patients with better baseline visual acuity.

Scientific reports·2024
Same author

Selective retina therapy with real-time feedback-controlled technology in central serous chorioretinopathy: a 24-month follow-up real-world prospective study.

BMJ open ophthalmology·2024
Same author

Volumetric fluid analysis of fixed monthly anti-VEGF treatment in patients with neovascular age-related macular degeneration.

International journal of ophthalmology·2023
Same author

Retinal vessel geometry in patients with idiopathic epiretinal membrane.

Scientific reports·2023
Same author

Vitreous Fatty Amides and Acyl Carnitines Are Altered in Intermediate Age-Related Macular Degeneration.

Investigative ophthalmology & visual science·2023

Area of Science:

  • Ophthalmology
  • Rheumatology
  • Surgical Science

Background:

  • Behçet's disease is a multisystem inflammatory disorder.
  • Persistent panuveitis is a common ocular manifestation of Behçet's disease.
  • Vitreoretinal complications can significantly impair vision in these patients.

Purpose of the Study:

  • To evaluate the safety and efficacy of vitrectomy for managing vitreoretinal complications in Behçet's patients.
  • To assess the impact of vitrectomy on visual acuity and inflammatory control.
  • To identify potential predictors of surgical success or failure.

Main Methods:

  • Retrospective review of patients with Behçet's panuveitis undergoing therapeutic vitrectomy.
  • Inclusion criteria: persistent uveitis despite maximal medical therapy.

Related Experiment Videos

  • Outcome measures: visual acuity improvement (0.3 logMAR), relapse rates, and complications.

    • Main Results:

    • Twenty-one patients were analyzed with a mean follow-up of 30 months.
    • Vitrectomy significantly improved visual acuity and inflammatory control in most patients.
    • Patients with optic disc neovascularization (NVD) did not experience visual or inflammatory improvement.
    • Postoperative elevated intraocular pressure was linked to intravitreal triamcinolone acetonide use.

    Conclusions:

    • Vitrectomy appears to be a safe and effective treatment for vitreoretinal complications in Behçet's panuveitis.
    • Patients with NVD represent a subgroup with potentially poor outcomes following vitrectomy.
    • Further research may be needed to optimize management strategies for NVD in Behçet's disease.