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Updated: Aug 14, 2026
A Non-invasive Way to Isolate and Phenotype Cells from the Conjunctiva
Published on: July 5, 2017
[Cytologic and histologic methods in the diagnosis of conjunctival lesions: comparative study]
Carlos Gustavo de Melo G Lima1, João Carlos Bezerra Veloso, Ana Daniele Tavares
1Fundação Altino Ventura, Recife, PE. carlosgustav@hotmail.com
Purpose:
To evaluate both the efficacy and reliability of the cytologic method in the diagnosis of conjunctival lesions and compare it with the histologic examination.
Methods:
A prospective study on 31 conjunctival lesions was performed. Samples were obtained with a Kimura spatula. The lesions were, then, surgically removed and sent for histologic examination. The Papanicolaou technique was used for the cytologic examination.
Results:
The cytologic method showed high specificity (100%) and sensitivity (92.9%). The positive predictive value was 100% and the negative was 94.4%.
Conclusions:
The simple cytologic method is effective and reliable for the diagnosis of tumoral lesions of the conjunctiva.
