Related Experiment Video
Updated: May 25, 2026

09:44
Neuro-rehabilitation Approach for Sudden Sensorineural Hearing Loss
Published on: January 26, 2016
Video-assisted subtotal or near-total thyroidectomy for Graves' disease
1Division of Endocrine Surgery, Department of Surgery, Nagasaki University Graduate School of Biomedical Sciences, 1-7-1 Sakamoto, Nagasaki, 852-8501, Japan. maedas@net.nagasaki-u.ac.jp
The British Journal of Surgery
|December 3, 2005
Summary
Video-assisted thyroidectomy offers a safe and effective surgical option for Graves' disease patients. This minimally invasive approach resulted in high patient satisfaction and minimal complications.
Area of Science:
- Endocrinology
- Surgical Oncology
- Minimally Invasive Surgery
Background:
- Graves' disease is a common autoimmune disorder leading to hyperthyroidism.
- Surgery is a primary treatment modality for Graves' disease, especially after medical or radioiodine therapy failure.
- Video-assisted thyroidectomy presents a minimally invasive alternative to traditional open surgery.
Purpose of the Study:
- To evaluate the efficacy and safety of video-assisted subtotal or near-total thyroidectomy for Graves' disease.
- To assess surgical outcomes, including complications, thyroid function, quality of life, and patient satisfaction.
Main Methods:
- A cohort of 63 patients with Graves' disease underwent video-assisted thyroidectomy between 2000 and 2004.
- The majority of patients (84%) had previously failed antithyroid drug and radioiodine therapy.
- Outcomes were comprehensively assessed, focusing on complications and patient-reported results.
Main Results:
- No conversions to open surgery were required, demonstrating the feasibility of the video-assisted technique.
- A low complication rate was observed, with only 5% experiencing temporary recurrent laryngeal nerve palsy.
- High patient satisfaction was reported, particularly concerning the cosmetic outcome of surgical scars.
Conclusions:
- Video-assisted subtotal or near-total thyroidectomy is a safe and effective surgical treatment for Graves' disease.
- The procedure offers a minimally invasive option with favorable patient outcomes and high satisfaction rates.
Related Concept Videos
Biosynthesis in Bacteria
1.0K
Biosynthesis in bacteria is a fundamental anabolic process that generates essential macromolecules, including proteins, nucleic acids, lipids, and polysaccharides. These macromolecules are critical for cellular growth, replication, and function. The process is tightly regulated and energetically linked to catabolic pathways to ensure optimal resource utilization.Biosynthetic pathways begin with precursor metabolites such as pyruvate, acetyl-CoA, and glucose-6-phosphate derived from glycolysis,...
1.0K
Biosynthesis of Polysaccharides
984
Polysaccharides such as glycogen and starch are synthesized from nucleoside diphosphate sugars, primarily uridine diphosphate glucose (UDPG) and adenosine diphosphate glucose (ADPG). These activated glucose donors act as key intermediates in carbohydrate metabolism and biosynthesis. UDPG primarily involves glycogen synthesis in animals and many bacteria, while ADPG plays a fundamental role in starch synthesis in plants and certain bacteria.UDPG is formed when glucose-1-phosphate reacts with...
984
Amino Acid Biosynthetic Pathways
1.8K
Amino acid biosynthesis is essential for cell growth, protein synthesis, and metabolic regulation. Cells generate essential and non-essential amino acids from metabolic intermediates to sustain vital biological functions. These intermediates originate from key metabolic pathways: glycolysis, the tricarboxylic acid (TCA) cycle, and the pentose phosphate pathway. Important precursors include α-ketoglutarate, pyruvate, oxaloacetate, phosphoenolpyruvate, and erythrose-4-phosphate, which...
1.8K
Bioreactor Controls-III
67
Strain improvement is a foundational strategy in industrial microbiology aimed at maximizing microbial productivity, particularly because natural isolates typically yield commercially valuable products in very low concentrations. Although optimizing the culture medium and environmental conditions can improve yields, these adjustments are inherently limited by the organism’s genetic potential. As a result, the focus shifts toward genetic modifications to enhance biosynthetic capacity. The...
67
Production of Antibiotics
265
Penicillin, one of the earliest and most widely used antibiotics, is produced industrially by the filamentous fungus Penicillium chrysogenum. Large stirred-tank bioreactors ranging from tens to hundreds of thousands of liters maintain tightly controlled temperature, pH, and dissolved oxygen conditions to support fungal metabolism and maximize antibiotic yield. Penicillin is a secondary metabolite, synthesized primarily during the stationary growth phase, which requires a carefully managed...
265

