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Related Experiment Videos

Nifedipine-induced gingival hyperplasia.

J Katz1, I Rotstein, A Ben Yehuda

  • 1Department of Oral Diagnosis, Hebrew University, Haddasah Faculty of Dental Medicine, Jerusalem.

Annals of Dentistry
|January 1, 1992
PubMed
Summary

Nifedipine medication can cause gingival hyperplasia, characterized by enlarged, bleeding gums. This adverse drug reaction may reverse with appropriate medication changes.

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Area of Science:

  • Dentistry
  • Pharmacology

Background:

  • Gingival hyperplasia is a known adverse effect of nifedipine, a calcium channel blocker.
  • Oral manifestations include gingival enlargement, pain, and spontaneous bleeding.

Observation:

  • Two cases of nifedipine-induced gingival hyperplasia are presented.
  • The clinical presentation and management of these cases are detailed.

Findings:

  • Nifedipine therapy can lead to significant gingival overgrowth.
  • Reversibility of gingival hyperplasia is possible with drug substitution.

Implications:

  • Highlights the importance of monitoring oral health in patients taking nifedipine.
  • Suggests alternative medications may be necessary to manage this side effect.

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