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Enterococcal resistance--an overview.

Y A Marothi1, H Agnihotri, D Dubey

  • 1Depatment of Microbiology, MGM Medical College, Indore-, Madhya Pradesh, India. dryogyata@yahoo.com

Indian Journal of Medical Microbiology
|December 6, 2005
PubMed
Summary
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Nosocomial infections caused by multidrug-resistant Enterococcus are a major patient safety concern. Vancomycin-resistant Enterococcus strains, often resistant to other antibiotics, pose significant therapeutic challenges and require control efforts.

Area of Science:

  • Microbiology
  • Infectious Diseases
  • Patient Safety

Background:

  • Nosocomial acquisition of multidrug-resistant microorganisms poses a significant threat to patient safety.
  • Enterococcus is a notable nosocomial pathogen, with increasing antimicrobial resistance.
  • The emergence of vancomycin-resistant Enterococcus (VRE) is particularly problematic due to co-resistance to ampicillin and aminoglycosides.

Purpose of the Study:

  • To review the issue of antimicrobial resistance in Enterococcus.
  • To highlight the challenges posed by vancomycin-resistant Enterococcus.
  • To emphasize the importance of controlling the prevalence of resistant strains.

Main Methods:

  • Literature review on antimicrobial resistance in Enterococcus.
  • Analysis of factors contributing to VRE colonization and infection.

Related Experiment Videos

  • Discussion of control strategies for resistant strains.

    • Main Results:

    • Enterococcus species are significant contributors to nosocomial infections.
    • Vancomycin resistance in Enterococcus, often combined with ampicillin and aminoglycoside resistance, leads to severe therapeutic consequences.
    • Multiple factors facilitate VRE colonization, infection, environmental contamination, and cross-infection.

    Conclusions:

    • Controlling the prevalence of vancomycin-resistant Enterococcus is crucial for patient safety.
    • Environmental contamination and cross-infection are key aspects of VRE spread.
    • Multifaceted control efforts are necessary to decrease the incidence of these resistant strains.