Related Experiment Videos
[Adult-onset Still disease with hemophagocytic syndrome treated with cyclosporine]
M Hamidou1, D Boutoille, A Masseau
1Service de médecine interne, CHU Hôtel-Dieu, Nantes (44). mohamed.hamidou@chu-nantes.fr
Introduction:
Adult-onset Still disease can have severe manifestations, the treatment of which is not yet codified.
Case:
The authors report a case of life-threatening adult-onset Still disease with hemophagocytic syndrome, which improved dramatically with cyclosporin A. Despite the presence of severe pancytopenia, adult-onset Still disease is suggested by the combination of sore throat, myalgia, rash, hepatitis, high serum ferritin, low glycosylated ferritin, and negative etiologic findings.
Discussion:
Still disease may be present in patients with febrile pancytopenia, and cyclosporine may be a useful treatment after corticosteroid failure.
Related Concept Videos
Drugs for Treatment of Crohn's Disease in IBD Using Immunomodulatory Agents
Cytomegalovirus Disease
Drugs for Treatment of Crohn's Disease in IBD Using Glucocorticoids
Drugs for Treatment of Crohn's Disease in IBD Using Biologic Agents: Anti-TNF
Nephrotic Syndrome II : Assessment and Medical Management
Cryptococcal Meningitis