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[Invasive schistosomiases].

S Jauréguiberry1, L Perez, L Paris

  • 1Service des maladies infectieuses et tropicales, Hôpital Tenon, Paris (75).

Presse Medicale (Paris, France : 1983)
|December 6, 2005
PubMed
Summary
This summary is machine-generated.

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Schistosomiasis is a tropical infection diagnosed in its invasive phase, presenting with flu-like symptoms and potential organ complications. Early diagnosis and corticosteroid treatment are crucial for severe cases, as standard medication may worsen outcomes.

Area of Science:

  • Tropical Medicine
  • Parasitology
  • Immunology

Context:

  • Schistosomiasis is a significant tropical helminthic infection affecting both travelers and endemic populations.
  • The invasive phase, occurring 2-6 weeks post-exposure, is characterized by acute parasitic toxemia, hypersensitivity reactions, and circulating immune complexes.

Purpose:

  • To detail the clinical presentation, diagnostic considerations, and treatment nuances of acute schistosomiasis.
  • To highlight the importance of considering schistosomiasis in travelers with compatible symptoms and hypereosinophilia.

Summary:

  • The invasive stage manifests with fever, fatigue, headache, gastrointestinal, respiratory, and dermatological symptoms, alongside potential neurological and cardiac complications.
  • Diagnosis involves clinical suspicion, delayed hypereosinophilia, seroconversion, and egg detection in stool or urine.

Related Experiment Videos

  • Standard praziquantel treatment is ineffective and potentially harmful in the acute phase; corticosteroids are recommended for severe manifestations.

    • Impact:

    • Emphasizes the need for timely and accurate diagnosis of schistosomiasis in returning travelers.
    • Informs clinical practice regarding appropriate management strategies for acute schistosomiasis, differentiating it from later stages.
    • Underscores the potential severity of schistosomiasis, including fatal neurological and cardiac complications, necessitating prompt recognition and tailored treatment.