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Published on: March 21, 2025
Out-of-plane computed-tomography-guided biopsy using a magnetic-field-based navigation system
Michael J Wallace1, Sanjay Gupta, Marshall E Hicks
1Department of Diagnostic Radiology, Section of Vascular and Interventional Radiology, The University of Texas M. D. Anderson Cancer Center, Houston, Texas, USA. mwallace@di.mdacc.tmc.edu
Cardiovascular and Interventional Radiology
|December 6, 2005
Summary
This study shows that magnetic-field-based navigation systems are effective for out-of-plane computed-tomography (CT)-guided biopsies. The system enabled accurate and safe biopsies of various lesions without complications.
Area of Science:
- Medical Imaging
- Interventional Radiology
- Oncology
Background:
- Out-of-plane computed-tomography (CT)-guided biopsies present technical challenges.
- Magnetic-field-based navigation systems offer potential solutions for improving biopsy accuracy and safety.
Purpose of the Study:
- To report clinical experience with out-of-plane CT-guided biopsies using a magnetic-field-based navigation system.
- To evaluate the technical success and complication rates of this novel approach.
Main Methods:
- Twenty patients underwent CT-guided biopsy using a magnetic-field-based navigation system for out-of-plane approaches.
- A coaxial needle system (18G outer, 22G inner) was employed for fine-needle aspiration.
- Lesions were located in adrenal glands, liver, pancreas, lung, lymph nodes, and pelvis.
Main Results:
- All 20 biopsies achieved successful needle tip positioning within the target lesions.
- A diagnosis of malignancy was obtained in 14 biopsies; benign diagnoses were found in 6.
- No complications were reported during or after the procedures.
Conclusions:
- Magnetic-field-based navigation systems are effective adjunct tools for CT-guided biopsies.
- This technology facilitates accurate and safe out-of-plane biopsy approaches for various lesions.
- The system demonstrated a high technical success rate and a favorable safety profile.

