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Updated: Jan 1, 2026

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Published on: January 22, 2022
Intraoperative consultation in gynecologic pathology
Donna Coffey1, Alan L Kaplan, Ibrahim Ramzy
1Departments of Pathology, The Methodist Hospital, Houston, Texas 77030, USA. dcoffey@tmh.tmc.edu
Intraoperative consultation for gynecologic specimens accurately identifies malignancy and assesses surgical margins. This frozen section technique is crucial for effective gynecologic cancer management.
Area of Science:
- Gynecologic Pathology
- Surgical Pathology
- Oncology
Background:
- Intraoperative consultation of gynecologic specimens is vital for confirming malignancy and assessing resection adequacy.
- Examination of surgical margins is a key component of this process.
Purpose of the Study:
- To review the application, indications, contraindications, and limitations of intraoperative consultation for gynecologic specimens.
- To discuss causes of false-positive and false-negative frozen section results.
Main Methods:
- Literature review.
- Expert and experienced-based analysis.
Main Results:
- Intraoperative consultation accurately determines malignancy type, margin status, and tumor extent in most cases.
- The technique is highly sensitive and specific for gynecologic disease.
Conclusions:
- Intraoperative consultation plays a critical role in managing gynecologic disease.
- Awareness of limitations is essential for both pathologists and surgeons.
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