Related Experiment Video
Updated: Aug 14, 2026

A Model of Long-Term Ventricular Fibrillation in Isolated Rat Hearts
Published on: February 17, 2023
Risk factors of ventricular tachyarrhythmias after coronary artery bypass grafting
Marco Budeus1, Peter Feindt, Emmeran Gams
1Department of Cardiology, West-German Heart Centre, University of Duisburg-Essen, Hufelandstr. 55, D-45122 Essen, Germany. marco.budeus@medizin.uni-essen.de
Insights
Predicting ventricular arrhythmias after coronary artery bypass grafting (CABG) is possible. A combination of ventricular late potentials, low ejection fraction, and reduced SDNN can identify high-risk patients for closer post-surgery observation.
Area of Science:
- Cardiology
- Cardiac Surgery
- Electrophysiology
Background:
- Ventricular arrhythmias (VA) are a rare but serious complication post-coronary artery bypass grafting (CABG).
- Identifying patients at risk for VA after CABG is crucial for improving patient outcomes.
Purpose of the Study:
- To identify predictors of ventricular arrhythmias in patients undergoing CABG.
- To develop a risk stratification model for post-CABG VA.
Main Methods:
- Retrospective study of 209 patients undergoing CABG with sinus rhythm.
- Analysis included signal-averaged ECG, standard deviation of normal RR intervals (SDNN), and echocardiographic data.
- Ventricular arrhythmias defined as sustained ventricular fibrillation or tachycardia.
Main Results:
- Ventricular arrhythmias occurred in 5% of patients post-CABG.
- Patients with VA had higher incidence of ventricular late potentials (91% vs 9%) and lower ejection fraction (44.2% vs 60.1%).
- A combination of ventricular late potentials, ejection fraction ≤38%, and SDNN ≤28 ms independently predicted VA (OR 26.00).
Conclusions:
- Ventricular arrhythmias after CABG can be predicted using signal-averaged ECG, ejection fraction, and SDNN.
- High-risk patients identified by these parameters require careful postoperative monitoring.
Background:
Ventricular arrhythmias are rare and represent the most serious arrhythmic complication after coronary artery bypass grafting (CABG).
Methods:
The present retrospective study was conducted for identifying patients at risk of ventricular arrhythmias with ventricular signal averaged ECG, standard deviation of all normal RR intervals (SDNN), angiographic and echocardiographic data. We defined ventricular arrhythmias as sustained ventricular fibrillation and ventricular tachycardia. The study population consisted of 209 consecutive patients with sinus rhythm undergoing CABG. The primary endpoint was the occurrence of VA after CABG. The secondary endpoints were hospital length of stay after CABG and the occurrence of VA after hospital discharge.
Results:
During the postoperative follow-up ventricular arrhythmias were observed in 11 patients (5%). Patients with ventricular arrhythmias showed a higher incidence of ventricular late potentials (91 vs. 9% of patients, p<0.0001) than patients without ventricular arrhythmias. In addition patients with ventricular arrhythmias had a lower left ventricular ejection fraction (44.2+/-15.2 vs. 60.1+/-13.1%, p<0.0001) and a SDNN (22.4+/-8.8 vs. 34.4+/-16.1 ms, p<0.02). A stepwise logistic regression analysis of all variables identified the combination of ventricular late potentials, ejection fraction < or = 38% and SDNN < or = 28 ms (odds rate 26.00; 95% CI, 3.44-196.67, p<0.002) as an independent predictor of ventricular arrhythmias.
Conclusions:
The results of our study suggest that the probability of ventricular arrhythmias could be predicted after CABG by a combination of low left ventricular ejection fraction and a measurement of ventricular signal averaged ECG and standard deviation of all normal RR intervals. Patients who can be identified as having a high risk of ventricular arrhythmias should be observed carefully after surgery.
More Related Videos
06:57Ablation of Ischemic Ventricular Tachycardia Using a Multipolar Catheter and 3-dimensional Mapping System for High-density Electro-anatomical Reconstruction
Published on: January 31, 2019
09:12Surgical Swine Model of Chronic Cardiac Ischemia Treated by Off-Pump Coronary Artery Bypass Graft Surgery
Published on: March 27, 2018
Related Concept Videos
Dysrhythmias II: Classification of Tachyarrhythmias
Mechanism of Cardiac Arrhythmias
Disturbances in Heart Rhythm
Arrhythmias are categorized by their speed, rhythm, and origin. A slow heart...
Dysrhythmias III: Characteristics of Dysrhythmias
ECG Interpretation of Arrhythmias II: Atrial, Junctional and Ventricular Arrhythmias
Coronary Artery Disease III: Clinical Manifestations