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Related Experiment Videos

Five-year experience with Crossfire highly cross-linked polyethylene.

James A D'Antonio1, Michael T Manley, William N Capello

  • 1Greater Pittsburgh Orthopaedics Association, Moon Township, PA 15108, USA. jadantonio@verizon.net

Clinical Orthopaedics and Related Research
|December 7, 2005
PubMed
Summary

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Highly cross-linked polyethylene hip bearings showed a 60% reduction in wear compared to conventional polyethylene. This advanced material offers a durable alternative for active patients, reducing osteolysis risk.

Area of Science:

  • Orthopedic Surgery
  • Biomaterials Science
  • Medical Device Technology

Background:

  • Total hip arthroplasty (THA) relies on bearing surfaces to minimize wear and osteolysis.
  • Conventional polyethylene inserts are prone to wear, potentially leading to implant loosening and revision.
  • Highly cross-linked polyethylene offers improved wear resistance compared to conventional materials.

Purpose of the Study:

  • To compare the clinical wear performance of highly cross-linked polyethylene (Crossfire) versus conventional polyethylene (N2Vac) in total hip replacements.
  • To evaluate the long-term efficacy and safety of Crossfire polyethylene in an active patient population.

Main Methods:

  • Retrospective comparative study of 56 hips with Crossfire liners and 53 control hips with conventional inserts.

Related Experiment Videos

  • Minimum 4-year, average 5-year follow-up with radiographic assessment of linear head penetration and wear.
  • Clinical data collection including complications and revision rates.

    • Main Results:

    • Crossfire polyethylene demonstrated a 60% reduction in linear femoral head penetration rate (0.055 mm/year vs. 0.138 mm/year).
    • Calculated annual wear was reduced by 72% for Crossfire components (0.036 mm/year vs. 0.131 mm/year).
    • Reduced erosive osteolytic lesions and debris release observed with Crossfire components; no revisions due to complications in either group.

    Conclusions:

    • Highly cross-linked polyethylene (Crossfire) significantly reduces wear in total hip arthroplasty compared to conventional polyethylene.
    • Crossfire offers a promising alternative bearing surface for active patients, potentially decreasing osteolysis and improving implant longevity.
    • Clinical outcomes support the use of this highly cross-linked polyethylene in total hip replacements.