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Updated: Aug 14, 2026

Echocardiographic Approaches and Protocols for Comprehensive Phenotypic Characterization of Valvular Heart Disease in Mice
Published on: February 14, 2017
[Prognostic value of stress echocardiography]
Roman Leischik1, Raimund Erbel
1Universität Witten-Herdecke. privat@dr-leischik.de
Stress echocardiography (SE) effectively identifies patients with coronary heart disease (CHD) who are at high risk for future cardiac events. Negative SE findings indicate a good prognosis, potentially reducing unnecessary invasive procedures and healthcare costs.
Area of Science:
- Cardiology
- Diagnostic Imaging
- Health Economics
Background:
- Chest pain assessment in outpatients is a common clinical challenge.
- Deciding between conservative or invasive strategies for chest pain management has significant implications.
- Coronary heart disease (CHD) diagnostics and prognostics present ongoing medical and economic challenges.
Purpose of the Study:
- To evaluate the prognostic significance of stress echocardiography (SE) in outpatients with chest pain.
- To determine if SE can effectively stratify risk and guide management decisions.
- To assess the potential of SE to reduce healthcare costs through selective invasive procedures.
Main Methods:
- Utilized stress echocardiography (SE) as a readily accessible, cost-effective, and familiar diagnostic tool.
- Analyzed cumulative data on the prognostic value of SE in patients with suspected CHD.
- Compared SE findings with patient outcomes and the need for invasive diagnostics.
Main Results:
- Patients with definitive ischemia detected by SE showed a 3-4 times higher incidence of cardiac events compared to those without.
- Negative SE findings were associated with a very good prognosis, often negating the need for invasive diagnostics.
- Consistent use of SE could identify high-risk patients, reducing invasive investigations.
Conclusions:
- Stress echocardiography is a valuable tool for risk stratification in outpatients with chest pain.
- SE can accurately identify patients likely to experience future cardiac events.
- Selective use of SE may lead to significant reductions in invasive procedures and associated healthcare costs.
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