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Updated: Jul 30, 2026

Pre-clinical Orthotopic Murine Model of Human Prostate Cancer
Published on: August 29, 2016
[Experience of brachytherapy using I-125 seed permanent implants for localized prostate cancer]
Kazuhito Toya1, Atsunori Yorozu, Toshio Ohashi
1Department of Radiology, National Hospital Organization Tokyo Medical Center.
Purpose:
We report here our experience of brachytherapy using I-125 seeds for localized prostate cancer in 100 patients.
Materials And Methods:
We carried out brachytherapy with I-125 seed permanent implants in 100 patients with localized prostate cancer between September 2003 and October 2004. Preplanning dosimetry was done using transrectal ultrasonic images obtained three or four weeks prior to treatment. Using transrectal ultrasound, we inserted I-125 seeds in the prostate through needles according to the preplanning diagram. We then examined the results on prostate CT performed one month later.
Results:
It was necessary to describe transrectal ultrasonic image such as preplanning. There were several cases in which the source arrangement of the schedule was corrected immediately before the operation. In the examination after one month, the numerical value at the start of treatment initially was not satisfactory, but we eventually obtained a result that could to be evaluated.
Conclusion:
We carried out permanent implant brachytherapy for localized prostate cancer using I-125 seeds and reported our experience.

