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Updated: Aug 14, 2026

Human Circadian Phenotyping and Diurnal Performance Testing in the Real World
Published on: April 7, 2020
[Chronobiology of pulp sensibility in young people]
Bin Guo1, Zhen Xu, Xiu-Mei Chen
1West China School of Stomatology, Sichuan University, Chengdu 610041, China.
Objective:
To explore the biological clock of pulp sensibility in young people so as to enrich the theory of pulp-chronobiology and conduce to clinical diagnosis and the treatment of pulposis.
Methods:
40 healthy young volunteers (20 males and 20 females) were examined. Pulp sensibility test was performed using the pulp sensibility tester produced in France. Pulp sensibility reading was obtained at each 4 hours from 8:00 a.m. till next 8:00 a.m., thus there were totally seven time-pints in 24 hours. And the readings were averaged.
Results:
The pulp sensibility data of every volunteer were analyzed by methods for cosinor-rhythmometry, and significant difference (P<0.05) was found. The acrophase and bathyphase appeared at 0:00 and 12:00 separately. We did not find significant difference of the mesor, amplitude and phase between young males and females (P> 0.05).
Conclusion:
Circadian rhythm is demonstrated in thepulp sensibility data of young people; the highest pulp sensibility is at 12:00 while the lowest is at 0:00.
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