Related Experiment Video
Updated: Aug 14, 2026
Application of Robot-assisted Pancreaticobiliary Junction Resection in Benign Duodenal Tumors
Published on: December 20, 2024
Long-term results of radical resection for locally advanced duodenal adenocarcinoma
Pascal Bucher1, Pascal Gervaz, Philippe Morel
1Clinic of Visceral and Transplantation Surgery, Department of Surgery University Hospital Geneva, Switzerland. Pascal.Bucher@hcuge.ch
Background/Aims:
Duodenal adenocarcinomas are uncommon tumors characterized by non-specific symptoms and late diagnosis. The objective of this study was to assess long-term results of locally advanced duodenal adenocarcinoma treated by surgical resection.
Methodology:
A retrospective study, over a 10-year period, identified 9 patients (mean age 65 years) treated for duodenal carcinoma.
Results:
Out of nine patients who were treated for duodenal adenocarcinoma, 8 underwent R0 resection (5 pancreaticoduodenectomies, 1 total pancreaticoduodenectomy and 2 segmental duodenal resections). All of them had tumor of stage II or III according to TNM classification. Median follow-up was 104 months (range 25 to 185). Five patients had lymph node metastases (stage III) at the time of surgery. Two- and five-year survival rates were 100% and 75%, respectively for the whole group. No correlation between lymph node status and survival was found.
Conclusions:
Radical surgical resection for locally advanced duodenal adenocarcinomas provides good long-term results in terms of patient survival, even for N1 tumors (stage III).
