Related Experiment Video
Updated: Aug 14, 2026
Intravascular Perfusion of Carbon Black Ink Allows Reliable Visualization of Cerebral Vessels
Published on: January 4, 2013
Hyperperfusion on perfusion computed tomography following revascularization for acute stroke
T B Nguyen1, C Lum, J D Eastwood
1Department of Radiology and Department of Neurology, Ottawa Hospital, Ottawa, Canada. thnguyen@ottawahospital.on.ca
Purpose:
To describe the findings of hyperperfusion on perfusion computed tomography (CT) in four patients following revascularization for acute stroke.
Material And Methods:
In 2002-2003, among a series of 6 patients presenting with an acute stroke and treated with intra-arterial thrombolysis, we observed the presence of hyperperfusion in 3 patients on the follow-up CT perfusion. We included an additional patient who was treated with intravenous thrombolysis and who had hyperperfusion on the follow-up CT perfusion. We retrospectively analyzed their CT perfusion maps. Cerebral blood volume (CBV) and cerebral blood flow (CBF) maps were compared between the affected territory and the normal contralateral hemisphere.
Results:
In the four patients, the mean CBV and CBF were 3.6 +/- 2.0 ml/100 g and 39 +/- 25 ml/100 g/min in the affected territory compared to the normal side (mean CBV = 2.7 +/- 2.1 ml/100 g, mean CBF = 27 +/- 23 ml/100 g/min). There was no intracranial hemorrhage in the hyperperfused territories. At follow-up CT, some hyperperfused brain areas progressed to infarction, while others retained normal white to gray matter differentiation.
Conclusion:
CT perfusion can demonstrate hyperperfusion, which can be seen in an ischemic brain territory following recanalization.
