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Chronic kidney disease: a European perspective
Norbert Lameire1, Kitty Jager, Wim Van Biesen
1EDTA/ERA Registry Academic Medical Center, Amsterdam, The Netherlands, and Department of Public Health University Hospital, Ghent, Belgium. norbert.lameire@ugent.be
Kidney International. Supplement
|December 13, 2005
Summary
Early detection of chronic kidney disease (CKD) is crucial. Identifying at-risk patients with kidney injury, even with normal renal function, can slow progression and prevent end-stage renal disease (ESRD).
Area of Science:
- Nephrology
- Public Health
- Renal Medicine
Background:
- Global rise in end-stage renal disease (ESRD) patients.
- Limited data on chronic kidney disease (CKD) prevalence and progression.
- Lack of international standards for renal function measurement hinders data collection.
Purpose of the Study:
- Highlight the impact of inadequate CKD follow-up on ESRD outcomes.
- Emphasize the significance of early detection and intervention for at-risk CKD patients.
- Promote the adoption of 'kidney injury' terminology for at-risk individuals.
Main Methods:
- Review of existing literature and data on CKD and ESRD prevalence and outcomes.
- Analysis of factors contributing to poor outcomes in ESRD patients.
- Discussion of the role of proteinuria and normal renal function in ESRD predisposition.
Main Results:
- Deficient follow-up in earlier CKD stages significantly contributes to poor ESRD outcomes.
- Proteinuria, even with normal renal function, is a risk factor for ESRD.
- Most CKD patients die before reaching ESRD, underscoring the importance of preventive measures.
Conclusions:
- Early detection of kidney injury is vital for implementing preventive measures.
- Slowing CKD progression can reduce the incidence of ESRD.
- Proactive management of CKD may paradoxically increase the observed ESRD patient numbers due to improved survival.