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Updated: Aug 14, 2026

Intramucosal Inoculation of Squamous Cell Carcinoma Cells in Mice for Tumor Immune Profiling and Treatment Response Assessment
Published on: April 22, 2019
Squamous cell carcinoma of the lower lip: exact location match in siblings
Dogan Tuncali1, Nurten Yavuz, Ahmet Terzioglu
1Department of Plastic and Reconstructive Surgery, Ankara Training and Research Hospital, Turkey. dogan_tuncali@yahoo.com
Background:
In recent years, genetic contribution to the development of skin cancers is under the magnifying glass of several authors and is now regarded as the main initial etiology in carcinogenesis.
Objective:
Two siblings who had squamous cell carcinoma of the lower lip showing an exact location match are presented.
Patients:
They did not share common environmental factors, and there was no history of tobacco and/or alcohol abuse.
Conclusions:
It would be scientifically deceptive to draw generous conclusions for the cases here, other than being a very interesting and unusual coincidence, because further evaluation could not be done to scientifically prove a possible genetic contribution.
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