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Amino acid pairing preferences in parallel beta-sheets in proteins

H M Fooks1, A C R Martin, D N Woolfson

  • 1School of Animal & Microbial Sciences, University of Reading, Whiteknights, P.O. Box 228, Reading RG6 6AJ, UK.

Journal of Molecular Biology
|December 13, 2005
PubMed
Summary

Statistical analysis reveals specific amino acid pairing preferences within parallel beta-sheets. These findings offer rules for protein structure prediction and engineering, based on hydrogen bonding and side-chain interactions.

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