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MRI study of corpus callosum in children and adolescents with bipolar disorder
A Sibel Yasar1, E Serap Monkul, Roberto B Sassi
1MOOD-CNS Program (Mood Disorders Clinical Neurosciences Program), Division of Mood and Anxiety Disorders, Department of Psychiatry, The University of Texas Health Science Center at San Antonio, TX 78229-3900, USA.
Abstract:
This structural magnetic resonance imaging study examined the length, areas, and circularity of the corpus callosum (CC) in 16 children and adolescents with bipolar disorder and 21 healthy controls. Bipolar disorder patients had lower circularity of the CC splenium compared with healthy controls. No significant differences in CC length or area were observed, suggesting that reported CC abnormalities appear late in the course of bipolar disorder.
