Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Search research articles

Related Experiment Videos

The CORRONA database.

Joel M Kremer¹

¹Albany Medical College, The Center for Rheumatology, Albany, New York 12203, USA. jkremer@joint-docs.com

Autoimmunity Reviews

|December 13, 2005

Summary

The CORRONA database provides crucial long-term safety and efficacy data for rheumatoid arthritis (RA) and psoriatic arthritis (PsA) treatments. This independent North American database offers insights beyond industry-sponsored studies.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

TWEAK receptor (Fn14) exacerbates TNF-α-induced inflammation in rheumatoid arthritis synovial fibroblasts and influences response to anti-TNF-α therapy.

Cellular & molecular immunology·2026

Same author

Psoriatic Arthritis Features and Risk of Cardiovascular Events: A Nationwide Cohort Study.

Cureus·2025

Same author

Development and External Validation of a Multivariable Predictive Model for Progression to Difficult-to-Treat Rheumatoid Arthritis in Biologic-Experienced Patients.

Arthritis care & research·2025

Same author

Disease response in rheumatoid arthritis across four biologic therapies associates with improvement in paraoxonase-1 activity and oxylipins.

RMD open·2024

Same author

Metabolic Syndrome, Adipokines, and Response to Advanced Therapies in Rheumatoid Arthritis.

Arthritis & rheumatology (Hoboken, N.J.)·2024

Same author

Effect of biologic agents and inflammation on lipid levels and cardiovascular risk in rheumatoid arthritis patients.

Seminars in arthritis and rheumatism·2024

Area of Science:

Rheumatology
Clinical Data Management
Pharmacovigilance

Background:

Long-term safety and efficacy data are essential for novel rheumatoid arthritis (RA) and psoriatic arthritis (PsA) treatments.
Existing industry-sponsored investigations offer limited scope for comprehensive data analysis.

Purpose of the Study:

To describe the structure, governance, content, context, and developmental plan of the CORRONA database.
To highlight the CORRONA database's role in advancing understanding of RA and PsA patient populations and treatment outcomes.

Main Methods:

The CORRONA database collects data from rheumatologists and patients during clinical encounters.
Data collection intervals are every 3 months for RA and every 6 months for PsA.
The database structure supports analysis of both common and rare adverse events.

Main Results:

Established in 2002, CORRONA is North America's largest independent database for RA and PsA.
Currently holds data on approximately 9,000 RA and 1,000 PsA patients.
Enables investigation of real-world prescribing patterns and treatment responses.

Conclusions:

After three years, the CORRONA database has matured into a valuable resource for RA and PsA research.
It significantly contributes to understanding drug safety, efficacy, and patient demographics.
The database is poised to yield substantial insights into managing these chronic conditions.

Related Experiment Videos