Related Experiment Video
Updated: Aug 14, 2026
A Multimodal Imaging- and Stimulation-based Method of Evaluating Connectivity-related Brain Excitability in Patients with Epilepsy
Published on: November 13, 2016
A comparative study of mismatch negativity (MMN) in epilepsy and non-epileptic seizures
Nuri Gene-Cos1, Richard Pottinger, Geoff Barrett
1Traumatic Stress Service, Clinical Treatment Center, Maudsley Hospital, London, UK. Nuri.Genecos@SLAM.nhs.uk
Abstract:
This study investigated mismatch negativity (MMN) differences between subjects with non-epileptic seizures (NES), subjects with epilepsy, and healthy controls. Event-related potentials (ERPs) were obtained from 14 patients with NES, 15 patients with epilepsy and 16 healthy control subjects. A conventional MMN procedure was used with a random sequence of 12% deviant tones (922 Hz) and 88% standard tones (1000 Hz). Subjects were instructed to ignore the tones delivered through headphones whilst reading a book. Significant differences in distribution of the mismatch negativity (MMN) in patients with NES compared to controls were obtained (F3, p
