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Updated: Aug 8, 2026

Collection, Isolation, and Flow Cytometric Analysis of Human Endocervical Samples
Published on: July 6, 2014
Microbiology profile in women with pelvic inflammatory disease in relation to IUD use
I Viberga1, V Odlind, G Lazdane
1Department of Women's and Children's Health, International Maternal and Child Health. i.viberga@apollo.lv
Objective:
To study the microbial characteristics of patients with pelvic inflammatory disease (PID) and the possible impact of an intrauterine device (IUD) on the microbial environment in women presenting with PID.
Methods:
Case-control study, investigating 51 women with acute PID and 50 healthy women. Endocervical specimens for microbiological investigation were obtained at gynaecological examination.
Results:
IUD users with PID had significantly more Fusobacteria spp. and Peptostreptococcus spp. than non-IUD users with PID. The finding of combinations of several anaerobic or aerobic microbes was associated with a significantly increased risk of PID and with complicated PID. In IUD users, the combinations of several anaerobic/aerobic microbes were associated with an increased risk of PID, irrespective of duration of IUD use. Long-term IUD use appeared to be associated with an increased risk of a PID being complicated.
Conclusion:
The finding of several anaerobic or aerobic microbes appears to be associated with PID in users of IUD.
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