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Acute anticholinergic poisoning in children
1Department of Paediatrics and Adolescent Medicine, Tuen Mun Hospital, Tuen Mun, Hong Kong. aclee@graduate.hku.hk
Hong Kong Medical Journal = Xianggang Yi Xue Za Zhi
|December 13, 2005
Summary
Unintentional anticholinergic poisoning in children can occur from prescribed medications or accidental ingestion. Prompt medical observation and fluid replacement led to spontaneous recovery in both reported cases.
Area of Science:
- Pediatric Toxicology
- Clinical Pharmacology
Background:
- Anticholinergic agents are commonly used medications with potential for toxicity.
- Unintentional poisoning in children presents a significant public health concern.
Observation:
- Two pediatric cases of anticholinergic poisoning are detailed: a 7-year-old girl prescribed multiple anticholinergic drugs and a 16-month-old boy who ingested cyproheptadine.
- Both children exhibited symptoms consistent with acute anticholinergic syndrome, including central and peripheral manifestations.
Findings:
- Spontaneous recovery was achieved in both cases with supportive care, including intravenous fluids and close monitoring.
- Gastric lavage was utilized in one case as an additional intervention.
Implications:
- This highlights the risk of anticholinergic toxicity in pediatric populations due to prescribing practices and household medication storage.
- Emphasizes the need for heightened awareness among healthcare providers and caregivers to prevent such poisoning incidents.