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Updated: Aug 14, 2026
11:36
In Vitro Ubiquitination and Deubiquitination Assays of Nucleosomal Histones
Published on: July 25, 2019
BAP1 and breast cancer risk
Isabelle Coupier1, Pierre-Yves Cousin, David Hughes
1Service de Génétique Oncologique, Institut Curie--Section Médicale, 26 rue d'Ulm, 75248, Paris, France. isabelle.coupier@curie.net
Familial Cancer
|December 13, 2005
Abstract:
BAP1 whose protein interacts with BRCA1 was analysed in a series of 47 French familial breast cancer cases negatively tested for BRCA1/2 mutations. The lack of detection of deleterious mutations suggests that BAP1 is not a high risk breast cancer predisposing gene. However, a common identified variant, rs123602, may be tested in sporadic cases as candidate for moderate risk.
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