Secondary prevention in coronary heart disease: goal achievement and drug prescribing
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Published on: May 14, 2013
Trude Giverhaug1, Christine Bruland, Thor Trovik
1Institute of Pharmacy, Faculty of Medicine, University of Tromsø, N-9037, Tromsø, Norway. trudeg@farmasi.uit.no
Insights
Treatment goal achievement for coronary heart disease (CHD) patients after percutaneous coronary intervention (PCI) was suboptimal. Improved drug prescribing and goal attainment are likely possible for CHD patients undergoing PCI.
Area of Science:
- Cardiology
- Clinical Practice
- Interventional Cardiology
Background:
- Coronary heart disease (CHD) management requires adherence to treatment guidelines.
- Percutaneous coronary intervention (PCI) is a common procedure for CHD patients.
- Assessing treatment goal achievement and drug prescribing is crucial for optimizing patient outcomes.
Purpose of the Study:
- To evaluate treatment goal achievement in CHD patients post-PCI.
- To analyze drug prescribing patterns in CHD patients undergoing PCI.
- To identify potential areas for improvement in clinical practice.
Main Methods:
- Retrospective study of 200 patients undergoing planned or acute PCI.
- Analysis of patient medical records and clinical chemistry data.
- Comparison of goal achievement and drug prescription against established therapeutic guidelines.
Main Results:
- Only 36% of patients achieved blood pressure goals (<140/90 mmHg) 3 months post-PCI.
- Cholesterol goals (<5 mmol/l) were met by 29% of patients at the time of PCI.
- Patients were prescribed an average of 1.4 antihypertensive drugs post-PCI; 78% received statins, 92% low-dose aspirin, and 23% diuretics.
Conclusions:
- Suboptimal achievement of treatment goals was observed in CHD patients post-PCI.
- Opportunities exist to enhance drug prescribing and improve goal attainment in this patient population.
- Clinical practice improvements are recommended for CHD patients undergoing PCI.
Objective:
To provide an overview of the degree of treatment goal achievement and drug prescribing in patients with coronary heart disease (CHD) in clinical practice.
Method:
Patients undergoing planned or acute percutaneous coronary intervention (PCI) were included. Patients' medical records and the hospital's database on clinical chemistry analyses were studied retrospectively.
Main Outcome Measure:
Goal achievement and drug prescription relative to published therapeutic guidelines.
Results:
A total of 200 patients aged 66 +/- 11 years were included. Blood pressure <140/90 mmHg was achieved in 36% of patients 3 months after PCI and total cholesterol <5 mmol/l was achieved in 29% at the time of PCI. Three months after PCI the patients were on 1.4 (range 0-4) drugs with antihypertensive effect (including diuretics). Seventy eight percent were on a statin, 92% were on low-dose aspirin, and 23% had a diuretic in their drug regimen. Five out of 16 patients with diabetes mellitus included in the study were prescribed an angiotensin converting enzyme-inhibitor (ACE-I).
Conclusion:
There is probably a potential for increased degree of goal achievement and for improved drug prescribing in patients with CHD undergoing PCI at our hospital.
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